I. FL series fluidized bed boiling drying granulator--Overview

The fluidized bed boiling drying granulator can complete the mixing, granulating and drying process in the same equipment, simplifying the process and meeting the GMP requirements of pharmaceutical production. The fluidized bed granulator system is used for particle coating, granulation and drying. In the field of pharmaceutical manufacturing, high coating uniformity and high yield are achieved in the final product. The material is fluidized and mixed under the action of the thrust of the air stream to form a fluidized state. The powder, the melt, and the aqueous medium are sprayed from top to bottom through the nozzle in the opposite direction to the direction of movement of the material.

Through the liquid bridge built by the surface tension of the liquid medium, the powder materials are bonded together to form a volume that is continuously enlarged, and finally a certain size of particles is formed and dried under the action of a hot air stream. The atomized binder bonds the fine powder to the fine powder to form a uniform particle and is dried by the action of hot air. The prepared particles have uniform particle size and good fluidity and compression moldability. The particle instant solution prepared by the fluidized bed granulator can also be used for capsule filling and tableting. It is an ideal choice for granulation, powder mixing and drying processes in the pharmaceutical, food, chemical and other industries. The equipment meets cGMP and FDA requirements.


2, FL series fluidized bed boiling drying granulator - characteristics


1. The inner surface of the device is smooth, smooth and free of dead ends, which makes the cleaning of the equipment easy and reliable;

2. Use air as power to avoid environmental pollution caused by liquid leakage when using liquid for power;

3. Temperature control: from room temperature to 100 °C. For heat sensitive items, a dehumidifier can be added to make a low temperature dry bath (35~40 °C);

4. The liquid material is used instead of alcohol as the wetting binder, and the new atomization system with stronger adaptability of the binder is used to improve the qualified rate of the finished product and reduce the production cost;

5. The air is pre-filtered and highly filtered to ensure the cleanliness of the hot air; the automatic switching of the two groups of valves allows the net movement of the particles to be uninterrupted. The working condition of negative pressure makes the drying of materials easier and more energy efficient;

6. Automation of operating procedures to reduce labor intensity. Man-machine interface control operation: parameters can be memorized, multi-layer password can be set, parameters can be controlled, and the display interface can be displayed. (eg temperature, time, pressure, air volume, absolute humidity, etc.);

7. Optional: WIP automatic cleaning device (or CIP device), pulse dust removal, anemometer, powder leak detector, suction device, vacuum discharge device (closed discharge), turning device for discharge, resistance Pressure 2Bar explosion-proof type and other functions.

8. The material is mixed, spray granulated, dried, granulated and coated in a closed container at one time. It can be used in a variety of models. Top spray granulation: powder granulation function; bottom spray Coating: It has the function of film coating and casing of sugar core (micropellet); side spray coating: it has the function of powder coating granulation/sugar (pellet) film coating and casing. Drying of the powder particles, powder granulation, granules of the granules (pellets), coating of the sugar cores (pellets), and coatings of the sugar cores (micropellets) can be carried out.